Superior Diagnostics, Targeted Treatments.

Next Generation Sequencing Is Now Available For Oral Health

"Recently, the next-generation sequencing (NGS) of bacterial 16S rRNA gene makes it possible to broaden our knowledge of the complexity of the microbiome, which has the advantage of detecting the composition of microbial communities in unprecedented depth."

Wei Y, Shi M, Zhen M, Wang C, Hu W, Nie Y and Wu X (2019) Comparison of Subgingival and Buccal Mucosa Microbiome in Chronic and Agressive Periodontitis: A. Pilot Study. Front. Cell. Infect. Microbiol. 9:53. doi: 10.3389/fcimb.2019.00053

Oral Health Test Service


Next-Gen DNA Sequencing (NGS) for Precise Microbial Diagnosis of Periodontal Infections

Special money-saving Introductory price available for Dentistry!

"Based on next-generation sequencing, novel microorganisms have been strongly associated with disease in addition to putative periodontal pathogens" (1)

Accurate microbial identification can be crucial to correctly treating patients with Periodontal Disease. PerioDX® with Next Generation Sequencing is superior technology available to you and your patients now

Journal of Dental Research 2019

Institute of Microbiology, Department of Medical Microbiology, Federal University of Rio de Janeiro, Brazil 2Department of Molecular Genetics. The Forsyth Institute, Cambridge, MA, USA 3Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA (1)

why You Need To Switch To PerioDX®

  • NGS is the most-advanced technology available for the Identification of microbes in disease, and for monitoring the progression in levels of microbes during a treatment plan.

  • Biofilms have a major impact on Periodontal disease. Only PerioDX using Next Generation Sequencing can identify the organisms contributing to biofilm formation and persistence.

  • Current saliva testing for Periodontal Disease, is limited to microbes in the panel tested. Disease-causing microbes can easily be missed using PCR alone.

  • PerioDX offers superior sampling method that offers you the flexibility to test saliva, periodontal pockets, or combine both samples for a comprehensive test result.

PerioDX vs. PCR Alone



  • Rapid Turn Around Time
  • Limited panel detects 8-35 of the most common species of microbes
  • May NOT detect species if mutated
  • Could miss dominant species within the infection

Next-Gen DNA Sequencing

  • Detects all Microbes including Aerobes, Anaerobes, Facultative anaerobes and Fungal Species
  • Can identify 50,000+ microbes with 99.9% accurate detection
  • Identifies all microbes by percentage of the unique DNA found in the sample
  • 6,500+ microbes identified in human tests to date

PerioDX® Reports combine highly-specific PCR technology and NGS technology for one comprehensive report

Our PCR panel contains 15 Bacteria associated with Periodontal disease, Plus Candida albicans.

about our tests

You can choose Saliva, or Saliva-Plus Pocket Sampling. In addition to saliva, we can process samples from deep in periodontal pockets.

This will give you a more comprehensive diagnostic result versus saliva alone. Combine both collection methods in one bio-hazard bag and this will be run as one test.


Is the world leader in Next Generation DNA Sequencing in the field of microbial identification.  MicroGenDx has published over 35 clinical trials and is the most experienced molecular diagnostic laboratory with over 500,000 NGS and 800,000 qPCR samples processed.

Latest From MicroGenDX®


Yes, just ensure that all of the samples are in ONE bio-hazard bag, and the lab requisition is included in the pocket. Learn more about how to sample areas of the mouth by visiting

View Our PerioDX Oral Health Lab Requisition PDF Here

Yes, you can put multiple samples in each FEDEX box and send them together. Learn more about our shipping process by visiting:

Log into the lab portal at to receive your results in 3-5 days.

We would love to hear from you if you have any questions about our oral health test kit at PerioDX. Please email [email protected], your satisfaction is important to us!

PerioDX Oral Health Test Service

Next-Gen DNA Sequencing (NGS) For Precise Microbial Diagnosis Of Periodontal Infections

Perio-Protect customers, please contact your representative for your coupon pricing discount code.

Call: 314-256-0772

Mail: [email protected]