Colorectal Cancer And Oral Microbiome​​​

  1. Castellarin, Mauro et al. “Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma.” Genome research vol. 22,2 (2012): 299-306. doi:10.1101/gr.126516.111
  2. Flemer, Burkhardt et al. “The oral microbiota in colorectal cancer is distinctive and predictive.” Gut vol. 67,8 (2018): 1454-1463. doi:10.1136/gutjnl-2017-314814
  3. Flynn, Kaitlin J et al. “Metabolic and Community Synergy of Oral Bacteria in Colorectal Cancer.” mSphere vol. 1,3 e00102-16. 11 May. 2016, doi:10.1128/mSphere.00102-16
  4. Koliarakis, Ioannis et al. “Oral Bacteria and Intestinal Dysbiosis in Colorectal Cancer.” International journal of molecular sciences vol. 20,17 4146. 25 Aug. 2019, doi:10.3390/ijms20174146
  5. Nosho, Katsuhiko et al. “Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.” World journal of gastroenterology vol. 22,2 (2016): 557-66. doi:10.3748/wjg. v 22.i2.557
  6. Sun, Chun-Hui et al. “The role of Fusobacterium nucleatum in colorectal cancer: from carcinogenesis to clinical management.” Chronic diseases and translational medicine vol. 5,3 178-187. 1 Oct. 2019, doi:10.1016/j. cdtm.2019.09.001
  7. Yang, Yaohua et al. “Prospective study of oral microbiome and colorectal cancer risk in low-income and African American populations.” International journal of cancer vol. 144,10 (2019): 2381-2389. doi:10.1002/ijc.31941
  8. Zhang, Sheng et al. “Human oral microbiome dysbiosis as a novel non-invasive biomarker in detection of colorectal cancer.” Theranostics vol. 10,25 11595-11606. 18 Sep. 2020, doi:10.7150/thno.49515
  9. Huh, Ji-Won, and Tae-Young Roh. “Opportunistic detection of Fusobacterium nucleatum as a marker for the early gut microbial dysbiosis.” BMC microbiology vol. 20,1 208. 13 Jul. 2020, doi:10.1186/s12866-020-01887-4
  10. Castellarin, Mauro et al. “Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma.” Genome research vol. 22,2 (2012): 299-306. doi:10.1101/gr.126516.111
  11. Flemer, Burkhardt et al. “The oral microbiota in colorectal cancer is distinctive and predictive.” Gut vol. 67,8 (2018): 1454-1463. doi:10.1136/gutjnl-2017-314814
  12. Flynn, Kaitlin J et al. “Metabolic and Community Synergy of Oral Bacteria in Colorectal Cancer.” mSphere vol. 1,3 e00102-16. 11 May. 2016, doi:10.1128/mSphere.00102-16
  13.  Koliarakis, Ioannis et al. “Oral Bacteria and Intestinal Dysbiosis in Colorectal Cancer.” International journal of molecular sciences vol. 20,17 4146. 25 Aug. 2019, doi:10.3390/ijms20174146
  14. Nosho, Katsuhiko et al. “Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.” World journal of gastroenterology vol. 22,2 (2016): 557-66. doi:10.3748/wjg. v 22.i2.557
  15.  Sun, Chun-Hui et al. “The role of Fusobacterium nucleatum in colorectal cancer: from carcinogenesis to clinical management.” Chronic diseases and translational medicine vol. 5,3 178-187. 1 Oct. 2019, doi:10.1016/j. cdtm.2019.09.001
  16. Yang, Yaohua et al. “Prospective study of oral microbiome and colorectal cancer risk in low-income and African American populations.” International journal of cancer vol. 144,10 (2019): 2381-2389. doi:10.1002/ijc.31941
  17.  Zhang, Sheng et al. “Human oral microbiome dysbiosis as a novel non-invasive biomarker in detection of colorectal cancer.” Theranostics vol. 10,25 11595-11606. 18 Sep. 2020, doi:10.7150/thno.49515
  18. Hussan, Hisham et al. “Fusobacterium‘s link to colorectal neoplasia sequenced: A systematic review and future insights.” World journal of gastroenterology vol. 23,48 (2017): 8626-8650. doi:10.3748/wjg. v 23. i48.8626
  19. Ito, M., Kanno, S., Nosho, K., Sukawa, Y., Mitsuhashi, K., Kurihara, H., Igarashi, H., Takahashi, T., Tachibana, M., Takahashi, H., Yoshii, S., Takenouchi, T., Hasegawa, T., Okita, K., Hirata, K., Maruyama, R., Suzuki, H., Imai, K., Yamamoto, H. and Shinomura, Y. (2015), Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway. Int. J. Cancer, 137: 1258-1268. 
  20. Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y. Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. World J Gastroenterol. 2016 Jan 14;22(2):557-66. doi: 10.3748/wjg. v 22. i2.557. PMID: 26811607; PMCID: PMC4716059.
  21. Xia, X., Wu, W.K.K., Wong, S.H. et al. Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome 8, 108 (2020).
  22. Yang, Yongzhi et al. “Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-κB, and Up-regulating Expression of MicroRNA-21.” Gastroenterology vol. 152,4 (2017): 851-866.e24. doi:10.1053/j. gastro.2016.11.018