The PerioDX Test is a major advance in microbial diagnostics in periodontal disease and oral health.
Both Polymerase Chain reaction (PCR) and Next Generation Sequencing (NGS) are used to analyze samples from saliva as well as periodontal pockets. The technology and the sampling method combine to give you a comprehensive report of your patient’s oral microbiome.
Page one of the PerioDX report shows you the results of the PCR analysis. PCR is a technology that makes many copies of a small portion of microorganisms’ genetic information. Results are limited to the number of microorganisms on the test panel. The PCR analysis in the PerioDX test is highly sensitive and specific for 15 bacteria and one fungus associated with periodontal disease. These organisms are:
PAGE TWO of the PerioDX report displays the results of the analysis of the Next-Generation Sequencing (NGS). Next-Generation Sequencing (NGS) analyzes the genetic fingerprint of everything in the sample. The genetic fingerprint is determined by comparing that to MicroGenDX’s curated library of DNA codes and then Bioinformatics software is used to identify the microbe. The comprehensive approach can identify thousands of possible microorganisms in one sample. Currently, MicroGenDx matches samples against a curated database of over 50,000 possible microbial DNA matches.
MicroGenDX provides an oral antibiotic guide with each report. You may download this guide here:
To share your PerioDX® report with a compound Pharmacy, please complete and return this form to MicroGenDX: